ConnectHEOR
- AI Engineering, Healthcare & Life Sciences
Client
ConnectHEOR
Location
London, UK
Engagement
AI Engineering and Healthcare & Life Sciences
Technologies & Tools Used
From weeks of manual modeling to AI-accelerated health economics.
ConnectHEOR is a global healthcare consultancy specializing in Health Economics and Outcomes Research.
It supports pharmaceutical and biotech firms with health economic modeling, real-world data analytics, evidence synthesis, market access strategies, and HEOR training.
The company combines deep domain expertise with responsible AI.
Building a GenAI platform for faster health economic model conceptualization.
Model conceptualization is the stage where a health economic model learns the disease pathway and its impact on patients.
At ConnectHEOR, this process was fully manual and took several weeks for each model.
That pace limited how many ideas the team could explore and how quickly models could be delivered.
Spark Eighteen helped ConnectHEOR automate health economic model conceptualization through a GenAI platform that produces its first version in hours instead of weeks.
The Challenge
ConnectHEOR needed to reduce the time required for model conceptualization while ensuring AI outputs reflected disease-specific pathways and worked effectively alongside domain experts.
Weeks Per Concept
Off-the-Shelf Fails
AI + Expert Workflow
The Solution
Spark Eighteen built a web-based GenAI tool trained on health economics data.
An agentic flow was co-designed with domain experts to divide conceptualization into smaller, solvable parts.
The LLM was grounded in a graph-database reasoning system using Graph of Thought, GraphRAG, and knowledge paths to reduce hallucinations.
A feedback loop was also added so models can be updated as experts provide input.
The Results
Economic modelers now co-build model concepts with AI.
A first version is produced in hours instead of weeks, while the final model is completed within weeks through the feedback loop.
The tool is used across teams and has received positive feedback at multiple HEOR conferences.
100%
6+
Business Outcomes
Collaborative AI Tool - Modelers and AI co-build conceptualizations in one place.
Accuracy Compounding - Continuous human feedback keeps improving reasoning.
Company-Wide Rollout - Teams across ConnectHEOR now use and test the tool.
Weeks to Hours - First model versions land the same day work begins.
Conference Credibility - Positive reception at multiple HEOR conferences.
Built to Extend - The platform is expanding toward a complete HEOR solution.
Spark Eighteen built a highly capable AI platform that changed the way we approach health economic modeling. Their team combined strong technical skills with a deep understanding of our domain to deliver a solution that is fast, accurate, and easy to use. The tool is now used across our teams and has received positive feedback at multiple HEOR conferences. We are excited to keep building with them and expand this into a complete HEOR solution.
